Causes Of Diabetes Mellitus
Blood sugar is regulated by two pancreatic hormones, namely insulin and glucagon. When blood sugar rises, ?
insulin is released; it binds to receptors and, through signal transduction, results in an increase in glucose uptake by cells, effectively lowering blood glucose. When blood sugar decreases, glucagon is released, binds to cell receptors, and causes glucose to be released into circulation. Diabetes mellitus is a disorder that results from excessively high levels of blood glucose. Type II diabetics have normal to elevated levels of insulin. What, then, might be causing the elevated blood glucose levels?
The elevated glucose level is caused by the inability of the cells to "take in " the glucose and use it for energy. The glucose continues to circulate in the blood. It is more a problem with the receptivity of the cells that with hormone imbalances.
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